Spirometry is a physiological procedure used as a diagnostic tool for disease diagnosis; e.g.
obstructive pulmonary diseases such as asthma or chronic obstructive pulmonary disease (COPD).
The bronchodilator test is a method of measuring lung capacity changes following inhalation of a
short-acting bronchodilator drug that dilates the airway, this test helps to diagnose, evaluate and
differentiate asthma from COPD.
Objective To evaluate the role of forced expiratory volume in third second (FEV3) as an alternative for forced
vital capacity (FVC) in assessing bronchodilator response in patients with chronic obstructive airway
diseases.
Methods The study a case-control, comparative study done from November 2018 to November 2019. The
cases involved divided into 2 groups; patients group included (80) patients with chronic obstructed
pulmonary diseases (asthma and COPD) and control group included (160) apparently healthy
peoples aged and sex matched. Lung function was measured using a standard protocol and
electronic table spirometry. Bronchodilator test was done for each patient with chronic obstructed
defect on spirometer.
Results There was no significant difference between (FVC), FVC% and (FEV3), FEV3% respectively before
bronchodilator and there was no significant difference after bronchodilator in patients. There was
no significant difference between FEV1/FVC, FEV1/FVC % and FEV1/ FEV3, FEV1/FEV3% respectively
before bronchodilator and there was no significant difference after bronchodilator in patients.
Conclusion FEV3 can be used as an alternative to FVC in patients with chronic obstructive airway diseases for
assessing bronchodilator response.
Keywords Spirometry, Bronchodilator test, FVC%, FEV3%, FEV1/FVC%, FEV1/FEV3%
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2020
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